Cellular and molecular mechanisms underlying synaptic plasticity

What We Study

Our lab investigates how neuronal activity and drug exposure alter synaptic plasticity, leading to long-lasting changes in synapse structure and function. These changes are central to processes such as learning and memory, neurodegeneration, and addiction. We are broadly interested in the cell biology of neurons and synaptic junctions, with a particular focus on the molecular mechanisms that govern the assembly, trafficking, and retention of proteins critical for neurotransmission and plasticity.

To address these questions, we use rodent cellular models and a range of molecular and biochemical approaches, with an emphasis on advanced fluorescence imaging techniques. Please visit the “Projects” section to learn more about our ongoing research.

Courses Taught

  • Introduction to Neuroscience

  • Neuroscience Research Methods

  • Conversations with Neuroscientists

  • Cellular Basis of Learning and Memory

Okunola Jeyifous, PhD (he/him)

Dr. Jeyifous joined the Department of Neuroscience in the College of Science and Health at DePaul University in 2022. He earned a BA in Neuroscience from Macalester College and a PhD in Neurobiology from the University of Chicago, where he trained with Dr. Bill Green. He completed his postdoctoral training with Dr. Craig Garner at Stanford University.

Fun facts: He is Nigerian-American, a stutterer, a twin dad, and a visual artist.